Tokyo: In a major medical breakthrough, Japanese researchers have successfully used stem cells to regenerate bone and heal spinal fractures in animal models. The innovative method, developed by scientists at Osaka Metropolitan University, uses stem cells derived from adipose tissue the body’s natural fat to rebuild damaged bones.
The research team extracted stem cells from fatty tissue and transformed them into bone-forming clusters, known as spheroids. When they implanted these into rats with spinal fractures, the animals showed remarkable recovery with stronger, regenerated bone tissue. The study, published in Bone and Joint Research, suggests a less invasive and highly effective alternative to traditional bone grafts or surgeries.
“These cells are easy to collect, even from older people, and place little stress on the body,” said Dr. Shinji Takahashi, one of the lead researchers. “This technique can heal complex fractures faster and more safely.”
The researchers found that the treatment activated key genes responsible for bone formation and regeneration. According to graduate researcher Yuta Sawada, the discovery opens new doors for developing regenerative treatments for osteoporosis-related fractures.
Osteoporosis makes bones fragile and prone to breaks, especially in the spine. The team’s new approach could significantly improve the quality of life for millions worldwide by reducing recovery time and minimizing surgical risks.
As the study moves toward clinical trials, scientists hope the use of stem cells to regenerate bone will soon become a viable therapy for humans, marking a new era in regenerative medicine.
–IANS
